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Primidone manufacturers India exporter cas No. 125-33-7 Primidone  suppliers from india companies Pharmaceuticals Drug from India Largest manufacturer Top Primidone import india Primidone export india Primidone buyer india Primidone seller India IP BP USP EP Primidone Raw material manufacturer india Primidone dealers india Primidone producer india Primidone API Active pharmaceuticals ingradients  Purchase Cheap Lowest Price COA MSDS certificate of Analysis wholesalers india Primidone suppliers india Primidone trader Drug india Primidone purchase india Primidone structure Primidone benefits Primidone pharmacy and drugs review api Primidone  active pharmaceutical ingredients suppliers pharmaceutical manufacturing pharmaceutical drugs pharmaceutical intermediates pharmaceutical chemicals pharmaceutical raw materials active pharmaceutical ingredients committee active pharmaceutical ingredients manufacturer construction chemicals manufacturers manufacturers of industrial chemicals chemicals suppliers chemicals Primidone  offers chemicals wholesalers exporters chemicals specialty chemicals chemicals Primidones indian chemical suppliers chemicals india company  Indian chemical manufacturers association chemical industries in India indian chemical company chemical factories india safety Primidones manufacturers India plastic Primidones manufacturers India definition of Primidone Primidone  synthesis Primidone  salt effects of Primidone clinical advantage of Primidone polymorphs of Primidone preparation of Primidone efficacy of Primidone beneficial effects of Primidone determination and validation of Primidone determination Primidone Primidone -Primidone side effect of Primidone polymorphs of Primidone level of Primidone Primidone process for preparing Primidone Primidone mg process for Primidone detailed info for Primidone catalog Primidone polymorphs of Primidone dosage of Primidone intermediate of Primidone Primidone powder supply Primidone Taj Pharmaceuticals Limited.
 

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Primidone CAS number 125-33-7

Primidone

CAS number 125-33-7Primidone Formula C12H14N2O2

Systematic (IUPAC) name
5-ethyl-5-phenyl-hexahydropyrimidine-4,6-dione

Identifiers
CAS number 125-33-7
ATC code N03AA03
PubChem 4909
DrugBank APRD00549
ChemSpider 4740

Chemical data
Formula C12H14N2O2
Mol. mass 218.252 g/mol
Pharmacokinetic data
Bioavailability ~100%
Protein binding 25%
Metabolism Hepatic
Half life Primidone: 5-18 hours,
Phenobarbital: 75-120 hours,
PEMA: 16 hours
Time to reach steady state:
Primidone: 2-3 days,
Phenobarbital&PEMA 1-4weeks
Excretion Renal

Primidone is an anticonvulsant of the pyrimidinedioneclass whose active metabolites, phenobarbitaland phenylethylmalonamide are also anticonvulsants. It is used mainly to treat complex partial, simple partials, generalized tonic-clonic seizures, myoclonic, akinetic seizures and  it has been a valuable alternative to propranolol in the treatment of essential tremor. Unlike other anticonvulsants such as carbamazepine and valproic acid, primidone is rarely used in the treatment of bipolar disorder or any other psychiatric problem. It is also not widely used in treatment of neuropathic pain, trigeminal neuralgia, or migraine. Primidone has been occasionally used to treat long QT syndrome, cerebral palsy, and athetosis.
Information Associated with Product:
DRUG DESCRIPTION
DOSAGE
SIDE EFFECTS
PRECAUTIONS
INTERACTION
CONSUMER INFORMATION
 
 
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